Within a week of writing about the weird paradoxical side effects I was getting from increasing my amitriptyline dose, things settled down considerably.
I’m still taking the increased dose of 30mg nightly (I take it around 8pm). In particular the return of a lot of my pain when increasing the dose was incredibly difficult to cope with. But sure enough that stopped.
I increased my dosage from 20mg to 30mg on 24th October. The side effects, most notably lots of pain, became much worse in the second week and peaked by the end of that week, the 7th November. By the end of week 3 it had settled down considerably.
Now, nearly 5 weeks after changing the dosage things are much better. I’m not sure the pain killing effect has increased dramatically (time will tell when I can look back at how often I’m getting migraines and so on). It’s difficult to know if it’s working or if I am not in pain anyway.
I do feel a bit more groggy first thing on waking than I did before the dosage increase. But that’s a lot easier than it was too. Maybe I need to take it a little earlier, or maybe it will settle in a week or so too.
What the 2 weeks of side effects reminded though was how bad things used to be before I started taking low dose amitriptyline for pain relief. It really does make a big difference. It doesn’t keep me totally pain free but life is a lot more comfortable and manageable with it.
Looks like persisting worked this time. Those weird side effects went after a few weeks – just like when I first started on 20mg.